MOTS-c

MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome, making it part of a unique class of mitochondrial-derived peptides (MDPs). Mitochondria are responsible for generating cellular energy, and emerging research suggests that MDPs such as MOTS-c play a role in supporting mitochondrial function, metabolic regulation, and cellular resilience under stress conditions. Studies have shown that MOTS-c levels rise in response to exercise, indicating potential involvement in adaptive metabolic processes. Scientific investigations have explored MOTS-c’s influence on metabolic flexibility, fatty acid utilization, glucose regulation, and mitochondrial energy pathways. Research models have examined its ability to modulate insulin sensitivity, support…